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Blue 2 Lake must be avoid by people with allergy reactions as it may cause skin sensitivity, a rash similar to nettle rash, high blood pressure, itching and breathing problems. (1)
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NutriBuddy™ 
Description
Blue 2 Lake is water soluble, organic salt derived from indigo by sulfonation. Commercially, it is produced synthetically from coal tar. It is deep blue dye that imparts a violet to blue shade in applications. It is approved to be used as a blue food colorant in the U.S and E.U. It is also used as a pH indicator.